US 7,462,705 B2
	Nucleic acids encoding an enediyne polyketide synthase complex
Chris M. Farnet, Outremont (Canada); Alfredo Staffa, Saint-Laurent (Canada); and Emmanuel Zazopoulos, Montreal (Canada)
Assigned to Thallion Pharmaceuticals Inc., (Canada)
Filed on Feb. 08, 2005, as Appl. No. 11/53,576.
Application 11/053576 is a continuation of application No. 10/152886, filed on May 21, 2002, granted, now 6,912,470.
Claims priority of provisional application 60/334604, filed on Dec. 03, 2001.
Claims priority of provisional application 60/291959, filed on May 21, 2001.
Prior Publication US 2005/0142601 A1, Jun. 30, 2005
Int. Cl. C07H 21/04 (2006.01)

U.S. Cl. 536—23.1

12 Claims

1. An isolated, purified or enriched nucleic acid encoding an enediyne polyketide catalytic complex comprising an enediyne polyketide synthase (PKSE) and a thioesterase (TEBC), wherein said PKSE comprises a C-terminal phosphopantetheinyl transferase (PPTE) domain.