US 7,461,045 B1
Optimization of spatio-temporal pattern processing for seizure warning and prediction
Wanpracha A. Chaovalitwongse, Hillsborough, N.J. (US); Leonidas D. Iasemidis, Scottsdale, Ariz. (US); Panos M. Pardalos, Gainesville, Fla. (US); James C. Sackellares, Gainesville, Fla. (US); and Deng-Shan Shiau, Gainesville, Fla. (US)
Assigned to University of Florida Research Foundation, Inc., Gainesville, Fla. (US); and Arizona Board of Regents, Scottsdale, Ariz. (US)
Filed on Aug. 18, 2004, as Appl. No. 10/920,446.
Claims priority of provisional application 60/495702, filed on Aug. 18, 2003.
Int. Cl. G06F 9/44 (2006.01); G06N 7/02 (2006.01); G06N 7/06 (2006.01)
U.S. Cl. 706—52 18 Claims
OG exemplary drawing
 
1. A computer-implemented method for predicting an impending seizure, comprising:
receiving dynamical measurement data regarding the system;
applying a quadratically constrained quadratic 0-1 program to identify data components among the received data, wherein the applying comprises linearizing the quadratically constrained quadratic 0-1 program, and wherein the linearizing comprises introducing a new 0-1 variable for each product of two variables and then formulating the quadratically constrained quadratic 0-1 program as a linear 0-1 problem;
storing the identified data components; and
predicting an impending seizure based on the identified data components.