US 7,459,528 B2
Glycoproteins which bind to TNF
Craig A. Smith, Seattle, Wash. (US); Raymond G. Goodwin, Seattle, Wash. (US); and M. Patricia Beckmann, Poulsbo, Wash. (US)
Assigned to Immunex Corporation, Thousand Oaks, Calif. (US)
Filed on Oct. 28, 2005, as Appl. No. 11/260,192.
Application 11/260192 is a division of application No. 10/420785, filed on Apr. 23, 2003, granted, now 7,057,022.
Application 10/420785 is a division of application No. 09/758124, filed on Jan. 12, 2001, granted, now 6,572,852.
Application 09/758124 is a division of application No. 08/953268, filed on Oct. 17, 1997, abandoned.
Application 08/953268 is a division of application No. 08/555629, filed on Nov. 09, 1995, abandoned.
Application 08/555629 is a division of application No. 08/468453, filed on Jun. 06, 1995, abandoned.
Application 08/038765 is a division of application No. 07/523635, filed on May 10, 1990, granted, now 5,395,760.
Application 08/468453 is a continuation of application No. 08/038765, filed on Mar. 19, 1993, abandoned.
Application 07/523635 is a continuation in part of application No. 07/421417, filed on Oct. 13, 1989, abandoned.
Application 07/421417 is a continuation in part of application No. 07/405370, filed on Sep. 11, 1989, abandoned.
Application 07/405370 is a continuation in part of application No. 07/403241, filed on Sep. 05, 1989, abandoned.
Prior Publication US 2006/0067934 A1, Mar. 30, 2006
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/715 (2006.01); C07K 14/435 (2006.01); A61K 38/16 (2006.01); C12P 21/02 (2006.01); C12N 15/09 (2006.01)
U.S. Cl. 530—350  [514/2; 514/12; 435/69.1; 435/325; 435/7.1] 30 Claims
 
1. An isolated glycoprotein that is capable of binding TNF, wherein said glycoprotein comprises amino acids 1-163 of SEQ ID NO:2 and is not isolated from human urine.