US 7,445,628 B2
	Method of treating a patient with a coated implantable medical device
Anthony O. Ragheb, West Lafayette, Ind. (US); Neal E. Fearnot, West Lafayette, Ind. (US); William D. Voorhees, III, West Lafayette, Ind. (US); Thomas G. Kozma, McHenry, Ill. (US); Brian L. Bates, Bloomington, Ind. (US); and Thomas A. Osborne, Bloomington, Ind. (US)
Assigned to Cook Incorporated, Bloomington, Ind. (US); and MED Institute, Inc., West Lafayette, Ind. (US)
Filed on Apr. 14, 2003, as Appl. No. 10/414,444.
Application 10/414444 is a continuation of application No. 10/223415, filed on Aug. 19, 2002.
Application 10/223415 is a continuation in part of application No. 09/027054, filed on Feb. 20, 1998, granted, now 6,774,278.
Application 09/027054 is a continuation in part of application No. 08/645646, filed on May 16, 1996, granted, now 6,096,070, filed on Aug. 01, 2000.
Application 08/645646 is a continuation in part of application No. 08/484532, filed on Jun. 07, 1995, granted, now 5,609,629, filed on Mar. 11, 1997.
Claims priority of provisional application 60/038459, filed on Feb. 20, 1997.
Prior Publication US 2004/0047909 A1, Mar. 11, 2004
Int. Cl. A61F 2/06 (2006.01)

U.S. Cl. 623—1.42  [424/471; 604/891.1; 623/1.44]

16 Claims

1. A method of treating a human or veterinary patient, comprising implanting a vascular stent at a point of treatment within the vascular system of a human or veterinary patient, the vascular stent comprising a surface, a coating layer consisting of a parylene polymer posited on the surface of the vascular stent, a layer comprising an immunosuppressive agent posited on at least a portion of the coating layer, and a porous layer comprising a second polymer overlaying the layer comprising the immunosuppressive agent.