US 7,605,260 B2
Process for producing imide compound
Yuzo Kakiya, Ibaraki (Japan); and Mayumi Oda, Osaka (Japan)
Assigned to Dainippon Sumitomo Pharma Co., Ltd., Osaka-Shi, Osaka (Japan)
Appl. No. 10/565,105
PCT Filed Jul. 27, 2004, PCT No. PCT/JP2004/011035
§ 371(c)(1), (2), (4) Date Jan. 19, 2006,
PCT Pub. No. WO2005/009999, PCT Pub. Date Feb. 03, 2005.
Claims priority of application No. 2003-281860 (JP), filed on Jul. 29, 2003.
Prior Publication US 2006/0194970 A1, Aug. 31, 2006
Int. Cl. C07D 241/04 (2006.01); C07D 295/00 (2006.01)
U.S. Cl. 544—358 2 Claims
 
1. A process for producing an imide compound hydrochloride of the formula (2):

OG Complex Work Unit Drawing
or an enantiomer thereof,which comprises treating a compound of the formula (1):

OG Complex Work Unit Drawing
or an enantiomer thereof with 1.8 to 5.0% aqueous hydrochloric acid solution in acetone, crystallizing the resultant hydrochloride of the formula (2), and isolating the crystallized hydrochloride of the formula (2).