US 7,605,129 B2
Splice variant of human placental growth hormone
Richard Joseph Fagan, 60 Charlotte Street, W1T 2NU (United Kingdom); Christopher Benjamin Phelps, 60 Charlotte Street, London W1T 2NU (United Kingdom); Tania Maria Rodrigues, 60 Charlotte Street, London W1T 2NU (United Kingdom); Christine Power, 10, rue des Jonquilles, F-01710 Thoiry (France); and Mariastella De Tiani, Rue des Sablons 6, CH-1205, Geneve (Switzerland)
Appl. No. 10/539,962
PCT Filed Dec. 19, 2003, PCT No. PCT/GB03/05594
§ 371(c)(1), (2), (4) Date Nov. 13, 2006,
PCT Pub. No. WO2004/056863, PCT Pub. Date Jul. 08, 2004.
Claims priority of application No. 0229850.3 (GB), filed on Dec. 20, 2002.
Prior Publication US 2007/0141569 A1, Jun. 21, 2007
Int. Cl. C07K 14/61 (2006.01); A61K 38/27 (2006.01)
U.S. Cl. 514—12  [514/2; 514/399] 26 Claims
 
1. An isolated polypeptide selected from the group consisting of:
a) a polypeptide comprising SEQ ID NO:8 or SEQ ID NO:10;
b) a polypeptide comprising a fragment of SEQ ID NO:8 or SEQ ID NO:10, wherein said fragment functions as a growth hormone;
c) a polypeptide consisting of SEQ ID NO:8 or SEQ ID NO:10;
d) a polypeptide that has greater than 96% identity to SEQ ID NO: 8 or SEQ ID NO: 10 and wherein said wherein said polypeptide functions as a growth hormone; and
e) a polypeptide comprising a fragment of the polypeptide according to d) and wherein said fragment functions as a growth hormone.