US 7,605,120 B2
Antagonists of the brandykinin B1 receptor
Gordon Ng, Newbury Park, Calif. (US); Benny C. Askew, Jr., Marshfield, Mass. (US); Derin C. D'Amico, Newbury Park, Calif. (US); Mark A. Jarosinski, Fishers, Ind. (US); and Chuan-Fa Liu, Waltham, Mass. (US)
Assigned to Amgen Inc., Thousand Oaks, Calif. (US)
Filed on Oct. 21, 2004, as Appl. No. 10/972,236.
Claims priority of provisional application 60/513913, filed on Oct. 22, 2003.
Claims priority of provisional application 60/538929, filed on Jan. 24, 2004.
Prior Publication US 2005/0215470 A1, Sep. 29, 2005
Int. Cl. A61K 38/08 (2006.01); A61K 38/10 (2006.01)
U.S. Cl. 514—2  [514/13; 514/15; 530/326; 530/328] 11 Claims
 
1. A peptide antagonist of the bradykinin B1 receptor comprising a sequence of amino acids selected from the group consisting of SEQ ID NOS: 15-18, 23, 25, 26, 39, 41, 45, 44, and 46-51, or a physiologically acceptable salt thereof.