US 7,598,403 B2
Synthesis of chromanones
Brian A. Salvatore, Shreveport, La. (US); and Ferdinand C. Solis, Lexington, S.C. (US)
Assigned to The University of South Carolina Research Foundation, Columbia, S.C. (US)
Appl. No. 10/557,065
PCT Filed May 17, 2004, PCT No. PCT/US2004/015418
§ 371(c)(1), (2), (4) Date Feb. 27, 2007,
PCT Pub. No. WO2004/103985, PCT Pub. Date Dec. 02, 2004.
Claims priority of provisional application 60/560208, filed on Apr. 07, 2004.
Claims priority of provisional application 60/471267, filed on May 16, 2003.
Prior Publication US 2007/0203214 A1, Aug. 30, 2007
Int. Cl. C07D 311/00 (2006.01)
U.S. Cl. 549—401  [549/403] 17 Claims
 
1. A chromanone corresponding to Formula 21:

OG Complex Work Unit Drawing
wherein
R5 is amino or nitro;
R6 is amino, hydroxy, halo, perfluorinated sulfonic ester, R61C(O)—, R62C(O)O—, R61C(O)NH—, R62CHCH— or R62CC—;
R21 and R22 are independently hydrogen, alkyl, or aryl;
R61 is hydrogen, heterocyclo, alkoxy, heterocyclooxy, amino, or halo, and
R62 is hydrogen, hydrocarbyl, substituted hydrocarbyl, heterocyclo, alkoxy, heterocyclooxy, amino, or halo.