US 7,585,673 B2
	γ-heregulin
Gabriele Maria Schaefer, San Francisco, Calif. (US); and Mark Sliwkowski, San Carlos, Calif. (US)
Assigned to Genentech, Inc., South San Francisco, Calif. (US)
Filed on Jul. 01, 2005, as Appl. No. 11/173,893.
Application 10/290578 is a division of application No. 09/514573, filed on Feb. 28, 2000, granted, now 6,500,941, filed on Dec. 31, 2002.
Application 11/173893 is a continuation of application No. 10/290578, filed on Nov. 08, 2002, granted, now 6,916,624, filed on Jul. 12, 2005.
Application 09/514573 is a continuation of application No. 08/891845, filed on Jul. 10, 1997, granted, now 6,096,873, filed on Aug. 01, 2000.
Claims priority of provisional application 60/021640, filed on Jul. 12, 1996.
Prior Publication US 2006/0029602 A1, Feb. 09, 2006
Int. Cl. A61K 38/18 (2006.01); A61K 38/17 (2006.01)

U.S. Cl. 435—377  [435/375; 435/7.21; 435/405; 530/399; 514/12]

8 Claims

1. A method for activating an ErbB receptor comprising contacting a cell which expresses an ErbB receptor with an isolated polypeptide having at least 95% sequence identity to a polypeptide comprising the amino sequence of SEQ ID NO:2, wherein the polypeptide stimulates tyrosine phosphorylation of the ErbB receptor.