US 7,585,646 B2
	Human GIL-19/AE289 polynucleotides and methods of producing the encoded polypeptides
Kenneth Jacobs, Newton, Mass. (US); Lynette Fouser, Acton, Mass. (US); Vikki Spaulding, Acton, Mass. (US); and Dejun Xuan, Clayton, Mich. (US)
Assigned to Genetics Institute, LLC, Cambridge, Mass. (US)
Filed on Dec. 17, 2004, as Appl. No. 11/13,920.
Application 11/013920 is a continuation of application No. 09/561811, filed on Apr. 28, 2000, granted, now 7,307,161.
Claims priority of provisional application 60/131473, filed on Apr. 28, 1999.
Prior Publication US 2005/0158760 A1, Jul. 21, 2005
This patent is subject to a terminal disclaimer.
Int. Cl. C12P 21/06 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 15/74 (2006.01); C07H 21/04 (2006.01)

U.S. Cl. 435—69.1  [435/252.3; 435/320.1; 435/325; 435/471; 536/23.5]

11 Claims

1. An isolated polynucleotide, comprising a nucleic acid sequence that hybridizes under conditions at least as stringent as 4×SSC at 65 degrees C. followed by washes at 65 degrees C. in 1×SSC, or 4×SSC with 50% formamide at 42 degrees C. followed by washes at 65 degrees C. in 1×SSC, to a complement of the polynucleotide having the nucleotide sequence of SEQ ID NO:1, wherein said nucleic acid sequence encodes a polypeptide that induces phosphorylation of a Stat3 polypeptide; and wherein the polypeptide encoded by the nucleic acid sequence comprises at least one amino acid sequence selected from: amino acids 50-60 of SEQ ID NO:2, amino acids 63-81 of SEQ ID NO:2, and amino acids 168-177 of SEQ ID NO:2.