US 7,585,296 B2
Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors
Stuart D Edwards, Portola Valley, Calif. (US); John Gaiser, Mountain View, Calif. (US); and David S Utley, San Carlos, Calif. (US)
Assigned to Mederi Therapeutics, Inc., Cos Cob, Conn. (US)
Filed on Sep. 20, 2005, as Appl. No. 11/230,801.
Application 11/230801 is a division of application No. 10/156505, filed on May 28, 2002, granted, now 6,974,456.
Application 10/156505 is a continuation of application No. 09/410448, filed on Oct. 01, 1999, granted, now 6,405,732.
Application 09/410448 is a continuation in part of application No. 09/026086, filed on Feb. 19, 1998, granted, now 6,006,755.
Prior Publication US 2006/0015162 A1, Jan. 19, 2006
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 18/18 (2006.01)
U.S. Cl. 606—41  [607/101] 2 Claims
OG exemplary drawing
 
1. A method comprising
detecting at a tissue site an electrical activity causing a transient relaxation of at least a portion of one of a sphincter, a lower esophageal sphincter, a stomach, a cardia, or a fundus,
treating the electrical activity at the tissue site by delivering electromagnetic energy to ablate at least a portion of one of the nerve, the gastric nerve, a nerve plexus, a myenteric nerve plexus, a ganglia, a nerve pathway or an electrically conductive pathway,
conducting a cooling solution to the tissue site at a flow rate,
measuring temperature at or near the tissue site,
comparing the measured temperature to a desired temperature,
increasing the flow rate of the cooling solution to the tissue site if the measured temperature exceeds the desired temperature, and
maintaining the flow rate of the cooling solution to the tissue site if the measured temperature does not exceed the desired temperature.