| US 7,572,591 B2 | ||
| Construct comprising recognition domain of antibody against von Willebrand factor-specific cleaving enzyme | ||
| Kenji Soejima, Kumamoto (Japan); Tomohiro Nakagaki, Kumamoto (Japan); Masanori Matsumoto, Nara (Japan); and Yoshihiro Fujimura, Nara (Japan) | ||
| Assigned to The Juridical Foundation Chemo-Sero-Therapeutic Research Institute, Kumamoto (Japan) | ||
| Appl. No. 10/549,317 PCT Filed Mar. 17, 2004, PCT No. PCT/JP2004/003602 § 371(c)(1), (2), (4) Date Sep. 16, 2005, PCT Pub. No. WO2004/083250, PCT Pub. Date Sep. 30, 2004. |
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| Claims priority of application No. 2003-071979 (JP), filed on Mar. 17, 2003. | ||
| Prior Publication US 2006/0240476 A1, Oct. 26, 2006 | ||
| Int. Cl. A61K 38/04 (2006.01); G01N 33/53 (2006.01) | ||
| U.S. Cl. 435—7.1 [530/324] | 4 Claims |
| 1. An isolated polypeptide consisting of the amino acid sequence from position 449 to position 687 in the amino acid sequence shown in SEQ ID NO. 1. |