| US 7,547,790 B2 | ||
| Optically active 4,4-di-substituted oxazolidine derivative and method for producing same | ||
| Toshihiko Onoda, Kanagawa (Japan); Yoshitaka Nakamura, Kanagawa (Japan); Makoto Yamaoka, Kanagawa (Japan); Tadahiro Takeda, Kanagawa (Japan); Noritada Sato, Kanagawa (Japan); and Masayoshi Jin, Kanagawa (Japan) | ||
| Assigned to Sankyo Company, Limited, Tokyo (Japan) | ||
| Appl. No. 11/664,053 PCT Filed Oct. 26, 2005, PCT No. PCT/JP2005/019678 § 371(c)(1), (2), (4) Date Mar. 30, 2007, PCT Pub. No. WO2006/046595, PCT Pub. Date May 04, 2006. |
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| Claims priority of application No. 2004-313183 (JP), filed on Oct. 28, 2004. | ||
| Prior Publication US 2008/0108828 A1, May 08, 2008 | ||
| Int. Cl. C07D 263/02 (2006.01); C07D 413/00 (2006.01) | ||
| U.S. Cl. 548—215 [548/100] | 17 Claims |
1. An optically active 4,4-di-substituted-oxazolidine compound having a formula (I)
 wherein
R1 represents a C1-C3 alkyl group which is substituted with one substituent from a Substituent group A, a C2 -C3 alkenyl group which is substituted with one substituent selected from the Substituent group A, a halogenated methyl group,
a hydroxymethyl group, a formyl group or a phosphonium methyl group,
R2 represents a C1-C6 alkyl group, a C3-C10 cycloalkyl group or a phenyl group,
R3 represents a methoxycarbonyl group,
R4 represents a C1-C6 alkyl group or a C2-C6 alkenyl group, the Substituent group A represents a phenyl group which is unsubstituted or substituted with from 1 to 3 substituents
selected from the group consisting of a halogen atom, a cyano group, a phenyl group, a C1-C8 alkyl group, a C1-C8 alkoxy group and a C2-C8 alkanoyl group; a thienyl group; a N-methylpyrrolyl group; or a furanyl group.
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