US 7,547,673 B2
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
Young He Ko, Pikesville, Md. (US); Jean-Francois H. Geschwind, Potomac, Md. (US); and Peter L. Pedersen, Columbia, Md. (US)
Assigned to The Johns Hopkins University, Baltimore, Md. (US)
Filed on Sep. 13, 2002, as Appl. No. 10/243,550.
Claims priority of provisional application 60/318710, filed on Sep. 13, 2001.
Prior Publication US 2003/0087961 A1, May 08, 2003
Int. Cl. A61K 38/16 (2006.01); A61K 38/21 (2006.01)
U.S. Cl. 514—1  [514/557; 514/171; 514/34] 13 Claims
 
1. A method of treating primary or secondary liver cancer in a subject comprising administering to a subject having a primary or secondary liver tumor an effective amount of a 3-halopyruvate or a salt thereof delivered by transcatheter hepatic intraarterial injection into the liver.