US 7,547,532 B2
	Three-dimensional structure of prostaglandin D synthase and utilization thereof
Yoshihiro Urade, Kyoto (Japan); Osamu Hayaishi, Kyoto (Japan); Tsuyoshi Inoue, Toyonaka (Japan); Yasushi Kai, Toyonaka (Japan); Yousuke Okano, Mino (Japan); Shigehiro Kinugasa, Itabashi-ku (Japan); Hiroyoshi Matsumura, Ibaraki (Japan); Daisuke Irikura, Mino (Japan); Masaki Yamamoto, Ako-gun (Japan); Takashi Kumasaka, Yokohama (Japan); and Masashi Miyano, Ibo-gun (Japan)
Assigned to Japan Science and Technology Agency, Kawaguchi-shi (Japan)
Appl. No. 10/495,218 PCT Filed Sep. 27, 2002, PCT No. PCT/JP02/09994 § 371(c)(1), (2), (4) Date Jul. 13, 2004, PCT Pub. No. WO03/042381, PCT Pub. Date May 22, 2003.
Claims priority of application No. 2001-346035 (JP), filed on Nov. 12, 2001.
Prior Publication US 2005/0255576 A1, Nov. 17, 2005
Int. Cl. C12N 9/00 (2006.01); C12N 9/02 (2006.01)

U.S. Cl. 435—183  [435/189]

1 Claim

1. An isolated non-crystalline complex consisting of human hematopoietic prostaglandin D synthase (PGDS) consisting of the amino acid sequence of SEQ ID NO: 1, glutathione and magnesium in a molar ratio of 2:2:1, which has the three dimensional structure shown by the structural coordinates in Table 2.