| US 7,473,698 B2 | ||
| Secondary amino anilinic piperidines as MCH1 antagonists and uses thereof | ||
| Mohammad R. Marzabadi, Ridgewood, N.J. (US); Yu Jiang, Jersey City, N.J. (US); Kai Lu, Lake Hiawatha, N.J. (US); Chien-An Chen, Flushing, N.Y. (US); John E. De Leon, North Bergen, N.J. (US); and John Wetzel, Fairlawn, N.J. (US) | ||
| Assigned to H. Lunbeck A/S, Valby - Copenhagen (Denmark) | ||
| Appl. No. 10/518,675 PCT Filed Jul. 03, 2003, PCT No. PCT/US03/21391 § 371(c)(1), (2), (4) Date Dec. 17, 2004, PCT Pub. No. WO2004/005257, PCT Pub. Date Jan. 15, 2004. |
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| Prior Publication US 2005/0245743 A1, Nov. 03, 2005 | ||
| Int. Cl. A61K 31/4465 (2006.01) | ||
| U.S. Cl. 514—331 [546/234] | 21 Claims |
1. A compound wherein the compound has the structure:
 wherein each A is independently —H, —F, —Cl, —Br, —I, —CN, —NO2, —OR3 or straight chained or branched C1-C7 alkyl;
wherein Z is CO or SO2;
wherein R4 is —COR3 or phenyl, wherein the phenyl is optionally substituted with one or more —F, —Cl, —Br, —I, —OR2, or straight chained or branched C1-C7 alkyl;
wherein each R3 is independently phenyl optionally substituted with one or more —F, —Cl, —Br, —I, —NO2, —CN, —OR2 or —NHR2;
wherein each R2 is independently straight chained or branched C1-C7 alkyl, or phenyl wherein the phenyl is optionally substituted with one or more —F, —Cl, —Br, —I, —NO2, or —CN; and
wherein n is an integer from 2 to 6 inclusive;
or a pharmaceutically acceptable salt thereof.
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